Human use of honey is traced to some 8000 years ago as depicted by Stone Age paintings. The ancient Egyptians, Assyrians, Chinese, Greeks and Romans employed honey for wounds and diseases of the gut .

The medical use of honey has been debated for thousands of years. The antiseptic and antimicrobial properties of honey have been explored and documented in numerous cultures throughout history.

The first recorded reference to medicinal honey dates back to the Sumerians at around 2000 BC. Archaeologists discovered a clay tablet in the Euphrates Valley containing the recipe for a wound treatment that included honey as an ingredient. From this point in history, applying honey to wounds as a topical healing salve or balm became the most commonly documented medicinal use of honey in cultures throughout the world.

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